Diagnostic Interpretation of Genetic Studies in Patients with Primary Immunodeficiency Diseases: A Working Group Report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma, and Immunology.

Genetic testing has become an integral component of the diagnostic evaluation of patients with suspected primary immunodeficiency diseases. Results of genetic testing can have profound impact on clinical management decisions. Clinical providers must therefore demonstrate proficiency in interpreting genetic data.

Because of the need for increased knowledge regarding this practice, the American Academy of Allergy, Asthma, and Immunology Primary Immunodeficiency Diseases Committee established a Work Group that reviewed and summarized information concerning appropriate methods, tools, and resources for evaluating variants identified by genetic testing. Strengths and limitations of tests frequently ordered by clinicians were examined.

Summary statements and tables were then developed to guide the interpretation process. Finally, the need for research and collaboration was emphasized. Greater understanding of these important concepts will improve the diagnosis and management of patients with suspected primary immunodeficiency diseases.

Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma & Immunology.

Providers caring for patients with mastocytosis are tasked with the decision to consider therapeutic options. This can come with some trepidation because information available in the public domain lists numerous mast cell (MC) activators based on data that do not discriminate between primates, rodents, and MC lines; do not consider dosage; and do not take into account previous exposure and resultant clinical findings.

anti-FBXW9
YF-PA21352	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to FBXW9

anti-FBXW9
YF-PA21353	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to FBXW9

FBXW9 Blocking Peptide
33R-7018	Fitzgerald	100 ug	EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FBXW9 antibody, catalog no. 70R-10074

Human FBXW9 shRNA Plasmid
20-abx963386	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

FBXW9 Recombinant Protein (Rat)
RP201086	ABM	100 ug	Ask for price

FBXW9 Recombinant Protein (Human)
RP058557	ABM	100 ug	Ask for price

FBXW9 Recombinant Protein (Mouse)
RP134171	ABM	100 ug	Ask for price

Polyclonal FBXW9 Antibody (N-term)
APR04215G	Leading Biology	0.1ml	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FBXW9 (N-term). This antibody is tested and proven to work in the following applications:

Fbxw9 ORF Vector (Rat) (pORF)
ORF067030	ABM	1.0 ug DNA	EUR 607.2

FBXW9 ORF Vector (Human) (pORF)
ORF019520	ABM	1.0 ug DNA	Ask for price

Fbxw9 ORF Vector (Mouse) (pORF)
ORF044725	ABM	1.0 ug DNA	EUR 607.2

FBXW9 sgRNA CRISPR Lentivector set (Human)
K0767801	ABM	3 x 1.0 ug	EUR 406.8

Fbxw9 sgRNA CRISPR Lentivector set (Rat)
K6502701	ABM	3 x 1.0 ug	EUR 406.8

Fbxw9 sgRNA CRISPR Lentivector set (Mouse)
K4917701	ABM	3 x 1.0 ug	EUR 406.8

FBXW9 sgRNA CRISPR Lentivector (Human) (Target 1)
K0767802	ABM	1.0 ug DNA	EUR 184.8

FBXW9 sgRNA CRISPR Lentivector (Human) (Target 2)
K0767803	ABM	1.0 ug DNA	EUR 184.8

FBXW9 sgRNA CRISPR Lentivector (Human) (Target 3)
K0767804	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Rat) (Target 1)
K6502702	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6502703	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Rat) (Target 3)
K6502704	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4917702	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4917703	ABM	1.0 ug DNA	EUR 184.8

Fbxw9 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4917704	ABM	1.0 ug DNA	EUR 184.8

FBXW9 Protein Vector (Human) (pPB-C-His)
PV078077	ABM	500 ng	Ask for price

FBXW9 Protein Vector (Human) (pPB-N-His)
PV078078	ABM	500 ng	Ask for price

FBXW9 Protein Vector (Human) (pPM-C-HA)
PV078079	ABM	500 ng	Ask for price

FBXW9 Protein Vector (Human) (pPM-C-His)
PV078080	ABM	500 ng	Ask for price

FBXW9 Protein Vector (Rat) (pPB-C-His)
PV268118	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Rat) (pPB-N-His)
PV268119	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Rat) (pPM-C-HA)
PV268120	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Rat) (pPM-C-His)
PV268121	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Mouse) (pPB-C-His)
PV178898	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Mouse) (pPB-N-His)
PV178899	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Mouse) (pPM-C-HA)
PV178900	ABM	500 ng	EUR 723.6

FBXW9 Protein Vector (Mouse) (pPM-C-His)
PV178901	ABM	500 ng	EUR 723.6

Fbxw9 3'UTR Luciferase Stable Cell Line
TU204534	ABM	1.0 ml	Ask for price

Fbxw9 3'UTR GFP Stable Cell Line
TU254534	ABM	1.0 ml	Ask for price

Fbxw9 3'UTR GFP Stable Cell Line
TU156468	ABM	1.0 ml	Ask for price

Fbxw9 3'UTR Luciferase Stable Cell Line
TU106468	ABM	1.0 ml	Ask for price

FBXW9 3'UTR GFP Stable Cell Line
TU057815	ABM	1.0 ml	EUR 1672.8

FBXW9 3'UTR Luciferase Stable Cell Line
TU007815	ABM	1.0 ml	EUR 1672.8

F-Box/WD Repeat-Containing Protein 9 (FBXW9) Antibody
abx029562-400ul	Abbexa	400 ul	EUR 627.6

F-Box/WD Repeat-Containing Protein 9 (FBXW9) Antibody
abx029562-80l	Abbexa	80 µl	EUR 343.2

FBXW9 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K0767805	ABM	3 x 1.0 ug	EUR 451.2

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6502705	ABM	3 x 1.0 ug	EUR 451.2

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K4917705	ABM	3 x 1.0 ug	EUR 451.2

Human F box/WD repeat containing protein 9(FBXW9) ELISA kit
E01F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box/WD repeat containing protein 9(FBXW9) ELISA kit
E01F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box/WD repeat containing protein 9(FBXW9) ELISA kit
E01F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E06F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E06F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E06F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E02F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E02F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box/WD repeat containing protein 9(FBXW9) ELISA kit
E02F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rat F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box/WD repeat containing protein 9(FBXW9) ELISA kit
E04F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box/WD repeat containing protein 9(FBXW9) ELISA kit
E04F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box/WD repeat containing protein 9(FBXW9) ELISA kit
E04F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box/WD repeat containing protein 9(FBXW9) ELISA kit
E08F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box/WD repeat containing protein 9(FBXW9) ELISA kit
E08F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Canine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box/WD repeat containing protein 9(FBXW9) ELISA kit
E08F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Canine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box/WD repeat containing protein 9(FBXW9) ELISA kit
E03F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box/WD repeat containing protein 9(FBXW9) ELISA kit
E03F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box/WD repeat containing protein 9(FBXW9) ELISA kit
E03F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E07F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E07F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E07F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine F- box/WD repeat- containing protein 9, FBXW9 ELISA KIT
ELI-48586b	Lifescience Market	96 Tests	EUR 1113.6

Human F- box/WD repeat- containing protein 9, FBXW9 ELISA KIT
ELI-48587h	Lifescience Market	96 Tests	EUR 988.8

FBXW9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K0767806	ABM	1.0 ug DNA	EUR 200.4

FBXW9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K0767807	ABM	1.0 ug DNA	EUR 200.4

FBXW9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K0767808	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6502706	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6502707	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6502708	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K4917706	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K4917707	ABM	1.0 ug DNA	EUR 200.4

Fbxw9 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K4917708	ABM	1.0 ug DNA	EUR 200.4

Monkey F box/WD repeat containing protein 9(FBXW9) ELISA kit
E09F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box/WD repeat containing protein 9(FBXW9) ELISA kit
E09F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box/WD repeat containing protein 9(FBXW9) ELISA kit
E09F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E05F0340-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E05F0340-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box/WD repeat containing protein 9(FBXW9) ELISA kit
E05F0340-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig F box/WD repeat containing protein 9(FBXW9) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

This being said, there is support in the literature for an enhanced MC response in some patients with mastocytosis and in cases in which there is a greater incidence of adverse reactions associated with certain antigens, such as venoms and drugs. Thus this report provides a comprehensive guide for those providers who must decide on therapeutic options in the management of patients with clonal MC disease.